500 Wilcox Street

Joliet, IL 60435

www.stfrancis.edu

 

ORGANIC CHEMISTRY II LAB

Spring 2008

CRN 20179

 

I. CH 03-227: 2 SEMESTER HOURS

SPRING SEMESTER 2008
COREQUISITE: CH 03-226
LAB HOURS: W 1:00-4:50 PM

 

II. INSTRUCTOR:Dr. Salim M. Diab
OFFICE: Room 215, St. Albert
PHONE: 740-3855 (Ext. 3855)
OFFICE HOURS: TTH 9:30-11:00 AM
HOME PHONE: 730-8302
E-mail: sdiab@stfrancis.edu
http://www.stfrancis.edu/ns/diab/etherman.htm

 

III. COURSE DESCRIPTION: A continuation of Organic Chemistry I Laboratory. The emphasis is on investigative organic synthesis, spectroscopy, synthesis,  qualitative identification of organic compounds, and research.

 

COURSE OBJECTIVES: Upon successful completion of this course, the student should be able to:
1. perform safely and successfully the various techniques learned in the first semester.
2. conduct organic chemistry experiments, follow procedures, use common sense, collect data, analyze data, and make sound conclusions.
3. use the chemical literature to search for essential information in organic chemistry.
4. keep organized and coherent documents of all that occurs in the laboratory.
5. appreciate the complexity and joy of planning, designing, and performing an organic synthesis.
6. utilize spectroscopic techniques to characterize purity and functionality of organic compounds.
7. identify the structures of unknown organic compounds utilizing wet chemistry and spectroscopic techniques.
8. appreciate the numerous and important applications of organic synthesis to our everyday life.

Web Reference: http://orgchem.colorado.edu/hndbksupport/ochemlabtech.html

IV. REQUIRED TEXT AND MATERIALS:
Organic Chemistry Lab CH 225/227, CER - Brooks/Cole Laboratory Series, 2006.

ISBN: 049507408-X

I. Spectroscopy:

IR (ATR) and NMR Spectroscopy - Theory and Interpretation of Structure - Read theory in TECH 710/711

Do pre-lab questions. Solve Supplementary Problems.  

 

II. Synthesis of Compounds of Medicinal and Biological Interest - Select only one experiment from each category below:

Note: Some of the experiments can be found in your lab manual while others need some research.

 

Category 1: Analgesics

SYNT 628 - Preparing Aspirin

SYNT 745 - Synthesizing Aspirin

SYNT 746 - Acetaminophen

SYNT 726 - Two Methods for the Synthesis of Phenacetin

Other?

 

Category 2:Anesthetics and Essential Oils/Fragrances

a. Synthesis of Benzocaine

b. Synthesis of Lidocaine

c. SYNT 713 - Synthesis of Fragrances

d. Other?

 

Category 3: Antiepileptic and Antimicrobial Drugs

a. Synthesis of Sulfa (Sulfanilamide)

b. Synthesis of Dilantin (Phenytoin)

c. Synthesis of Juglone

d. Other?

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III. Identification of Unknowns: Organic Qualitative Analysis: You will receive two unknowns. One is a liquid and the other is a solid. Your task is to use any physical or chemical tests from ANAL 727 to elucidate the chemical structure of your unknowns. Follow procedures carefully and use common sense. I am not looking for guess structures of your unknowns, but rather a logical and systematic analysis of your unknowns by the various physical and chemical tests. Once finished, you may check your results with IR (ATR) spectra. Report your results on the forms supplied by instructor. Best of Luck!

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IV. Investigative Research Project (sign up for a conference with me ASAP) ______________________________________________________________________

V. EXPECTATIONS OF STUDENTS:
1. Attendance is required. NO MAKE UP unless there is a justifiable conflict.
2. Computer generated lab reports are due for all experiments.
3. All products must be handed in to your instructor.
4. Nobody is allowed to work in the lab without permission and supervision.
5. Community Service: Science Fair Judging to local schools as needed.
6. Breakdown for grading:

Lab Reports ---- 40%

Unknowns ------ 30%

I – Research ---- 30%

Total --------------100%

7. Criteria used to arrive at the final grade: See Rubrics below

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Rubrics for Organic Chemistry Lab. Reports

 

Rubric

(4)Excellent

(3)V. Good

(2) Good

(1) Fair

1. Your name, title, date

 

 

 

 

 

2. Objective/Purpose

 

 

 

 

 

3. Introduction/Theory

 

 

 

 

 

4. Experimental

(materials, chemicals, instruments, procedure, etc.)

 

 

 

 

5. Data and Calculations

(tables, graphs, spectra, etc.)

 

 

 

 

6. Results and Discussion

(observations, conclusions, etc.)

 

 

 

 

7. Answers to Pre- lab questions and problems

 

 

 

 

8. Correct identification of unknowns

 

 

 

 

9. References

 

 

 

 

 

10. Investigative Research and Presentation

 

 

 

 

 

11. Overall evaluation

 

 

 

 

 

 

Academic Integrity

Academic integrity requires that all academic work be wholly the product of an identified individual or individuals. Collaboration is only acceptable when it is explicitly acknowledged. Ethical conduct is the obligation of every member of the University community, and breaches of academic integrity constitute serious offenses.  Since a lack of integrity hinders the students academic development, it cannot be tolerated under any circumstances. Violations include but are not limited to: cheating, fabrication, plagiarism, and denying others access to information or material. See USF Catalog for further clarification and information on grievance procedures..

Laboratory Notebook

Purpose: A laboratory notebook has three main purposes:

1. To keep relevant data and observations for your personal references;
2. To be able to duplicate the same experiment as it was reported;
3. To establish the validity of the work being done and of patent claims in a research lab.

General Guidelines for Organizing Your Lab Report:

http://www.stfrancis.edu/ns/diab/orglabreport.htm

Special Needs

The University strives to be in compliance with Americans with Disabilities Act (ADA) regulations. Students with disabilities who require reasonable accommodations to fully participate in course activities or meet course requirements are encouraged to register with the Office of Disability Services to discuss access issues.? Please call 815-740-5060 or visit the Library? L 214 to coordinate accommodations.

FINAL NOTE: The Writing Lab is an important resource on campus and is located in the ARC offices in the Library. Visit the Center and find out how its staff can help you with the writing assignments.

As a Catholic university rooted in the liberal arts, we are a welcoming community of learners challenged by Franciscan values and charism, engaged in a continuous pursuit of knowledge, faith, wisdom, and justice, and ever mindful of a tradition that emphasizes reverence for creation, compassion, and peacemaking. We strive for academic excellence in all programs, preparing women and men to contribute to the world through service and leadership.